(D-Phe12) bombesin and substance P analo
โ
Zul Merali; Carol A. Merchant; Jacqueline N. Crawley; David H. Coy; Peter Heinz-
๐
Article
๐
1988
๐
John Wiley and Sons
๐
English
โ 676 KB
The potency of synthetic bombesin (BN) analogues with D-Phe12 substitutions and substance P analogues was investigated in the rat CNS. (D-Phe12,Leu14)BN, (D-Phe12)BN and (Tyr4,D-Phe12)BN inhibited binding to rat brain slices with IC50 values of approximately 2 microM. Similarly, spantide inhibited b