Dermatology/Plastic surgery

• Publisher: John Wiley and Sons
• Year: 2005
• Tongue: English
• Weight: 201 KB
• Volume: 36
• Category: Article
• ISSN: 0196-8092
• DOI: 10.1002/lsm.20164

✦ Synopsis

In human tissue, components like collagen and elastic fibres, flavins and some proteins are strongly autofluorescent when excitated by ultraviolet radiation. Its native fluorescence are presented in 450 to 500 nm region (blue-green). When any constitutional tissue alteration occurs, pathological or not, its autofluorescence will be modified. Thus, this optical phenomenom can be considered a reliable diagnostic method. Study Design: Clinical preliminary. Aim: This works aims to study different sites of oral mucosa, comparing their native fluorescences spectra. Material and Method: 50 adults, healthy. The fluorescence spectra were obtained using a ''plug-in'' spectrometer (PC2000-S and Software OOIBase 32 TM ) and optical fiber. The native fluorescence were observed in six different sites of oral cavity, using a UV light, this prototype was manufaturing with KOMLUX.

Results and Discussion: 300 spectra were collected and shows the same grafical characteristics. The fluorescence intensity had different degree, according the sites and mucosal type.

Conclusion:

The similarity of preliminary results, as well for different mucosa sites, lead us to consider to stablish a standard for native fluorescence spectra of oral mucosa.