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Preliminary investigative studies with PDT in dermatologic and plastic surgery

✍ Scribed by Dr. Leon Goldman; Richard O. Gregory; Mary La Plant


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
233 KB
Volume
5
Category
Article
ISSN
0196-8092

No coin nor oath required. For personal study only.

✦ Synopsis


PDT has been shown to be of value in inoperable basal and squamous skin cancers and in cutaneous metastases. Azone, a new investigative vehicle for HpD, is of value more for intralesional injections than for topical applications in tumors, except perhaps for superficial mucous membrane lesions. The more flexible gold head vapor is of definite value in the PDT program.

For test models for PDT studies in dermatology and plastic surgery with HpD and other fluorochromes, single thickened resistant plaques of psoriasis and the common baso squamous acanthoma (seborrheic warty growth) have been used. In all these studies, adequate controls are necessary.