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Derivatives of pyrazinecarboxylic acid: 1H, 13C and 15N NMR spectroscopic investigations

✍ Scribed by Wolfgang Holzer; Gernot A. Eller; Barbara Datterl; Daniela Habicht

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
159 KB
Volume
47
Category
Article
ISSN
0749-1581

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✦ Synopsis

Abstract

NMR spectroscopic studies are undertaken with derivatives of 2‐pyrazinecarboxylic acid. Complete and unambiguous assignment of chemical shifts (^1^H, ^13^C, ^15^N) and coupling constants (^1^H,^1^H; ^13^C,^1^H; ^15^N,^1^H) is achieved by combined application of various 1D and 2D NMR spectroscopic techniques. Unequivocal mapping of ^13^C,^1^H spin coupling constants is accomplished by 2D (δ,J) long‐range INEPT spectra with selective excitation. Phenomena such as the tautomerism of 3‐hydroxy‐2‐pyrazinecarboxylic acid are discussed. Copyright © 2009 John Wiley & Sons, Ltd.

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