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Derivatives of 10,11-dihydro-5H-dibenzo[a,d]cycloheptene and related compounds VII. Improved syntheses of 11-h-benzo[5, 6] cyclohepta-[1,2-c] pyridin-11-one

โœ Scribed by Frank J. Villani; Elizabeth A. Wefer; Thomas A. Mann; Joseph Mayer; Lydia Peer; Alfred S. Levy


Book ID
112122808
Publisher
Journal of Heterocyclic Chemistry
Year
1972
Tongue
English
Weight
329 KB
Volume
9
Category
Article
ISSN
0022-152X

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The carbanion derived from 8,1 l-dichloro-6,1 l-dihydro-5H-benzo [5,6]cyclohepta[l,2-bl pyridine (3) reacts with methyl acrylate to form the C. spirocyclopropane carboxylic acid methyl ester 6. Compound 6 was converted in five steps to the N-methyl 2'-ethylamino spirocyclopropane 2 (R=H) which was r