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Derivation of Dihedral Angles from CH–CH Dipolar–Dipolar Cross-Correlated Relaxation Rates: A C–C Torsion Involving a Quaternary Carbon Atom in Epothilone A Bound to Tubulin

✍ Scribed by Teresa Carlomagno; Víctor M. Sánchez; Marcel J. J. Blommers; Christian Griesinger


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
133 KB
Volume
42
Category
Article
ISSN
0044-8249

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Derivation of Dihedral Angles from CH–CH
✍ Teresa Carlomagno; Víctor M. Sánchez; Marcel J. J. Blommers; Christian Griesinge 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB

Cross-correlated relaxation (CCR) rates constitute a valid alternative to coupling constants for the determination of dihedral angles. [1] For high-molecular-weight systems the measurement of scalar coupling constants poses serious problems caused by large linewidths and by differential relaxation e