✦ LIBER ✦

Derivate natürlicher Tetrapyrrole, Synthese einiger Modellverbindungen für die Photodynamische Therapie

✍ Scribed by Mackenbrock, Ursula ;Risch, Nikolaus

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 506 KB
Volume: 1991
Category: Article
ISSN: 0947-3440
DOI: 10.1002/jlac.1991199101116

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✦ Synopsis

Natural Tetrapyrrol Derivatives, Synthesis of Some Model Compounds for the Photodynamic Therapy

In photodynamic therapy, di‐ and polymeric porphyrins with ether, ester or direct CC linkages are the active components of hematoporphyrin derivative. Here we describe the synthesis of some new model compounds for such ether/ester dimers.

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Natural Tetrapyrrol Derivatives for the Photodynamic Therapy, 2. — Model Reactions for Direct C–C Linkages of Porphyrins Until now, there is a lack of information about the structure of the active components in the diagnosis and photodynamic therapy of cancer with hematoporphyrin derivatives (HPD).