✦ LIBER ✦

Depression in vascular dementia

✍ Scribed by Paul Naarding; Inge de Koning; Fop van Kooten; Diederik W. J. Dippel; Joost G. E. Janzing; Rose C. van der Mast; Peter J. Koudstaal

Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 64 KB
Volume: 18
Category: Article
ISSN: 0885-6230
DOI: 10.1002/gps.831

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Objective

To study the presence of different dimensions of depression in subjects with vascular dementia.

Background

After a stroke, cognitive, affective and behavioural disturbances are common. It has been suggested that the nature of affective symptomatology can help to differentiate organic from psychological depression.

Methods

Cognitive and affective symptoms were assessed in 78 stroke patients and a principal component analysis was performed on these symptoms. Also, a discriminant analysis was carried out to establish the contribution of different symptoms on the diagnosis ‘depressive disorder’ and ‘dementia’.

Results

(1) Principal component analysis revealed three distinct sub‐syndromes: one with predominantly mood symptoms, one with essentially psychomotor symptoms, and one with vegetative symptoms; (2) mood, psychomotor and vegetative symptoms were all independently and strongly related to a diagnosis of major depressive disorder according to DSM‐III‐R criteria; (3) the psychomotor factor was also firmly associated with dementia; and (4) discriminant analysis gave further support for our conclusion that some of the depressive features, in particular the psychomotor factor, are at least partly related to the organic brain damage from stroke.

Conclusion

The results indicate that different dimensions of depression could be discerned in a group of stroke patients and that the symptom profile of depression in these patients can be affected by the presence of dementia. Copyright © 2003 John Wiley & Sons, Ltd.

📜 SIMILAR VOLUMES

Moclobemide treatment of resistant depre

Moclobemide treatment of resistant depression in a patient with vascular dementia

✍ Yoram Barak; Hanna Suholitsky; Shlomo Noy 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 198 KB 👁 2 views

Patients suffering from dementia exhibit depressive symptoms in up to 86 per cent of cases. Syndromes meeting the criteria for major depression are more likely to respond to pharmacological therapy. Increased activity of M A 0 found in demented subjects make the treatment with MAO-inhibitors an obvi

Depression in dementia sufferers

✍ C.G. Ballard; C. Bannister; F. Oyebode 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 856 KB

A large number of studies concerning depression in dementia sufferers have appeared in the literature over the last few years and have added to our knowledge considerably. The prevalence rate of concurrent depression and dementia among clinical samples is approximately 20% with lower rates in the co

Vascular Dementia

✍ S. KNEZEVIC 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 67 KB

Vascular dementia

✍ Gustavo C. Román 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 104 KB

Depressive disorders in dementia

✍ Luca Rozzini; Barbara Vicini Chilovi; Maddalena Riva; Marco Trabucchi; Alessandr 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 71 KB

Subcortical symptoms predominate in vasc

Subcortical symptoms predominate in vascular dementia

✍ Anders Wallin; Kaj Blennow; Carl-Gerhard Gottfries 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 757 KB

Thirty-one patients with the clinical diagnosis of vascular dementia were examined with regard to symptoms reflecting disturbances in various brain regions. Frontal, parietal, subcortical and non-regional symptom complexes were used to characterize each patient. Frontal (77%) and subcortical (68%) s