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Dependence on interferon-γ for the spontaneous occurrence of arthritis in DBA/1 mice

✍ Scribed by Patrick Matthys; Rik J. Lories; Bert De Klerck; Hubertine Heremans; Frank P. Luyten; Alfons Billiau


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
143 KB
Volume
48
Category
Article
ISSN
0004-3591

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We examined host ability to produce a-and y-interferon on a large scale by culturing 2 rnl of peripheral blood for 20 hr with Sendai virus or concanavalin A as inducer of a-or yinterferon, respectively. Production of y-but nota-interferon was lower in females (n = 351) than in males (n = 531) (P < 0