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Deoxyverrucosidin, a Novel GRP78/BiP Down-regulator, Produced by Penicillium sp.

โœ Scribed by Choo, Soo-Jin; Park, Hae-Ryong; Ryoo, In-Ja; Kim, Jong-Pyung; Yun, Bong-Sik; Kim, Chang-Jin; Shin-ya, Kazuo; Yoo, Ick-Dong

Book ID
109867633
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
102 KB
Volume
58
Category
Article
ISSN
0021-8820

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โœ Hae-Ryong Park; Kazuo Furihata; Yoichi Hayakawa; Kazuo Shin-ya ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 115 KB

We discovered a novel down-regulator of grp78 gene expression designated as versipelostatin from the culture broth of Streptomyces versipellis 4083-SVS6. Its structure was determined to be a macrocyclic compound consisting of an a-acyltetronic acid and sugar moieties.