✦ LIBER ✦

Deoxyuridine triphosphate nucleotidohydrolase of HeLa cells

✍ Scribed by Suneeta Mahagaokar; Potu N. Rao; Antonio Orengo

Publisher: Elsevier Science
Year: 1980
Tongue: English
Weight: 650 KB
Volume: 11
Category: Article
ISSN: 0020-711X
DOI: 10.1016/0020-711x(80)90312-2

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Down—Regulation of Human Deoxyuridine Tr

Down—Regulation of Human Deoxyuridine Triphosphate Nucleotidohydrolase (dUTPase) Using Small Interfering RNA (siRNA)

✍ M. V. Williams; A. W. Studebaker 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 8 KB 👁 1 views

Flexible glycine rich motif of Escherich

Flexible glycine rich motif of Escherichia coli deoxyuridine triphosphate nucleotidohydrolase is important for functional but not for structural integrity of the enzyme

✍ Beata G. Vertessy 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 233 KB

Deoxyuridine triphosphate nucleotidohydrolase (dUTPase), a ubiquitous enzyme of DNA metabolism, has been implicated as a novel target of anticancer and antiviral drug design. This task is most efficiently accomplished by X-ray crystallography of the relevant protein-inhibitor complexes. However, the

Crystallization and preliminary investig

Crystallization and preliminary investigation of single crystals of deoxyuidine triphosphate nucleotidohydrolase from Escherichia coli

✍ Dr. Eilia S. Cedergren-Zeppezauer; Gunilla Larsson; Ingrid Hoffmann; Karl W. Tör 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 563 KB

Deoxyuridine triphosphate nucleotidohydrolase (dUTPase), an enzyme in the nucleotide metabolism that is a pyrophosphatase hydrolyzing dUTP, has been crystallized. The crystals belong to the trigonal space group R3 and diffract beyond 2 A. The native dUTPase crystals and a mercury derivative are stab

Effect of cytosine arabinoside triphosph

Effect of cytosine arabinoside triphosphate on the incorporation of 3H-thymidine in mitochondria isolated from HeLa cells

✍ L. Pica Mattoccia; R. Sorrentino 📂 Article 📅 1979 🏛 John Wiley and Sons 🌐 English ⚖ 442 KB 👁 1 views

## Abstract HeLa cell mitochondria were allowed to incorporate ^3^H‐thymidine in a cell free system and the effect of ethidium bromide, cytosine arabinoside and cytosine arabinoside triphosphate on the labeling of mitochondrial DNA was studied. The labeled products, isolated by sedimentation veloci

Simple synthesis of 5-vinyl- and5-ethyny

Simple synthesis of 5-vinyl- and5-ethynyl-2′-deoxyuridine-5′-triphosphates

✍ Teréz Kovács; Lázló Ötvös 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 225 KB

Acid-sensitive nucleoside 5'-0-triphosphates can be obtained in good yield directly from the unprotected nucleosides in the presence of a proton sponge. In the last decade, numerous pyrimidine nucleoside analogues have proven to be remarkably potent and selective in their activity against herpes si

Effect of mithramycin on HeLa cells

✍ Magnhild Sandberg-Wollheim; John W. Yarbro; B. J. Kennedy 📂 Article 📅 1968 🏛 John Wiley and Sons 🌐 English ⚖ 317 KB 👁 2 views