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Deoxyribonucleoside 3′-phosphorobisamidites in the synthesis of isopropyl phosphotriester oligodeoxyribonucleotide analogues

✍ Scribed by Kazushige Yamana; Yoshitaka Nishijima; Kazuo Negishi; Tetsuya Yashiki; Ken-ichi Nishio; Hidehiko Nakano; Osamu Sangen


Book ID
104225238
Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
291 KB
Volume
32
Category
Article
ISSN
0040-4039

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✍ Hideo Hosaka; Testuo Watanabe; Yoshikazu Suzuki; Hiroshi Takaku 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 609 KB

## The deoxyribonucleoside 3'-bis(l ,I ,I ,3,3,3-hexafluoro-2-propyl) phosphite units (3) are used in the chemical synthesis of oligodeoxyribonucleotides on solid supports. The new phosphite units (3) were prepared easily by reaction of nucleosides and tris-( I ,I ,I ,3,3,3-hexafluoro-2-propyl) phos