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Deoxypolynucleotides-purification of trinucleotide blocks by solvent extraction

✍ Scribed by Vipin Kohli; Ashok Kumar

Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
124 KB
Volume
87
Category
Article
ISSN
0037-9646

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✦ Synopsis

Abstract

Two protected trinucleotide blocks MMTr‐T~p~T~p~T and d‐MMTr‐A^Bz^~p~T~p~G^i‐Bu^ were synthesized using phosphodiester approach. The purification of these blocks was achieved in satisfactory yields simply by extraction into a binary organic solvent.

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