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Dentition of a 48,XYY,+21 male

✍ Scribed by Grant Townsend


Publisher
Springer
Year
1982
Tongue
English
Weight
165 KB
Volume
61
Category
Article
ISSN
0340-6717

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## Abstract During a routine ultrasound study on a fetus at 21 weeks, nuchal edema was noted. At 21 weeks, repeat ultrasound study at our unit showed scalp and neck edema and a femur length/biparietal diameter ratio below the mean. Transabdominal chorionic villus sampling identified a 48.XYY, + 21

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In the mouse XYY males are sterile, presumably because pairing abnormalities resulting from the presence of three sex chromosomes lead to meiotic breakdown. We have produced male mice, designated XYY\*X, that have three sex chromosomes pairing regions but only one intact Y chromosome. Unexpectedly X