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Prenatal diagnosis of 48,XYY, + 21 ascertained through ultrasound anomalies

✍ Scribed by Gollop, Thomaz Rafael ;Naccache, Nadyr F. ;Auler-Bittencourt, Eloisa ;Hauschild, Decio ;Eigier, Alberto ;Zveibil, Deborah K.


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
189 KB
Volume
39
Category
Article
ISSN
0148-7299

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✦ Synopsis


Abstract

During a routine ultrasound study on a fetus at 21 weeks, nuchal edema was noted. At 21 weeks, repeat ultrasound study at our unit showed scalp and neck edema and a femur length/biparietal diameter ratio below the mean. Transabdominal chorionic villus sampling identified a 48.XYY, + 21 chromosome constitution. The fetus had normal internal/external genitalia and signs of Down syndrome.