Dendritic cell regulation of TH1-TH2 development
β Scribed by Moser, Muriel; Murphy, Kenneth M.
- Book ID
- 109829039
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 212 KB
- Volume
- 1
- Category
- Article
- ISSN
- 1529-2908
- DOI
- 10.1038/79734
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π SIMILAR VOLUMES
The T helper (Th) phenotypes, Th1/Th2, are acquired upon interaction of a naive T helper cell and an antigen presenting cell (APC). Naive T helper cells may differentiate into either phenotype, and the actual outcome is determined by the density and avidity of the antigenic determinants presented by
## Abstract We characterized dendritic cells (DC) phenotypically and functionally between C57BL/6 (Th1βprone) and BALB/c (Th2βprone) mouse recipients in an in vivo sensitization model. Two strains of mice were presensitized with Lewis rat splenocytes as xenogeneic antigens. We found that BALB/c rec