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Dendritic-cell interactions with HIV: infection and viral dissemination

✍ Scribed by Wu, Li; KewalRamani, Vineet N.

Book ID
109955564
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
460 KB
Volume
6
Category
Article
ISSN
1474-1741

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Dendritic cells (DCs) and follicular dendritic cells (FDCs) play important roles in HIV-mediated pathogenesis. Recent studies have defined new DC subsets and shown that DCs in lymphoid mucosa can both harbor virus and stimulate its spread into CD4 + T cells. FDCs harbor unspliced HIV mRNA and immune