Dendritic cell-based cancer immunotherapy
โ Scribed by Edgar G Engleman
- Book ID
- 114106620
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 222 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0093-7754
No coin nor oath required. For personal study only.
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## Abstract ## BACKGROUND A promising treatment approach for patients with malignant disease that recently has found its way into clinical trials is based on vaccination with autologous dendritic cells loaded with tumor antigens. However, adequate assays for monitoring clinical and immunologic res
Over the years, the unique capacity of dendritic cells (DC) for efficient activation of naive T cells has led to their extensive use in cancer immunotherapy protocols. In order to be able to fulfil their role as antigen-presenting cells, the antigen of interest needs to be efficiently introduced and