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Adjuvant effect of a natural TLR4 ligand on dendritic cell-based cancer immunotherapy

✍ Scribed by Jee Youn Kim; Yeon Jin Kim; Ji Sung Kim; Hwa Sun Ryu; Hong Kyung Lee; Jong Soon Kang; Hwan Mook Kim; Jin Tae Hong; Youngsoo Kim; Sang-Bae Han


Book ID
116335756
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
535 KB
Volume
313
Category
Article
ISSN
0304-3835

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## Abstract Immunostimulatory DNA containing unmethylated cytosine‐guanine (CpG) motifs have been successfully used as adjuvants to enhance the immunity of vaccines designed to trigger antitumor T‐cell responses. We examined the effect of a CpG oligodeoxynucleotide (CpG ODN) for its ability to pote