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Dendritic and tumour cell -derived exosomes as novel cancer vaccines

✍ Scribed by L. Zitvogel; A. Lozier; J. Wolfers; A. Regnault; C. Masurier; N. Fernandez; G. Raposo; S. Amigorena

Book ID
117667436
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
169 KB
Volume
35
Category
Article
ISSN
0959-8049

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✍ Taylor, D D; GerΓ§el-Taylor, C πŸ“‚ Article πŸ“… 2005 πŸ› Nature Publishing Group 🌐 English βš– 158 KB

Dendritic and lymphoid β€˜exosomes’ regulate immune activation. Tumours release membranous material mimicking these β€˜exosomes,’ resulting in deletion of reactive lymphocytes. Tumour-derived β€˜exosomes’ have recently been explored as vaccines, without analysis of their immunologic consequences. This inv