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Demonstration on Pilot-Plant Scale of the Utility of 1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD) as a Catalyst in the Efficient Amidation of an Unactivated Methyl Ester

✍ Scribed by Weiberth, Franz J.; Yu, Yong; Subotkowski, Witold; Pemberton, Clive


Book ID
118064574
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
744 KB
Volume
16
Category
Article
ISSN
1083-6160

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1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD
✍ Iuliana Cota; Francisco Medina; JesΓΊs E. Sueiras; Didier Tichit πŸ“‚ Article πŸ“… 2011 πŸ› Elsevier Science 🌐 French βš– 716 KB

In this work it was shown that TBD (1,5,7-triazabicyclo[4.4.0]dec-5-ene), a cheap and commercially available guanidine base, efficiently catalyzes aldol condensation reactions yielding interesting products for pharmacological and fragrance industries. This methodology works under solvent-less condit