𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Demonstration of tumor suppression by mannose 6-phosphate/insulin-like growth factor 2 receptor

✍ Scribed by Li, Jin; Sahagian, G Gary


Book ID
110069104
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
409 KB
Volume
23
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Soluble insulin-like growth factor II/ma
✍ Carolyn D. Scott; Jocelyn Weiss πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 172 KB πŸ‘ 1 views

The soluble form of the insulin-like growth factor II (IGF-II)/mannose 6-P (IGF-II/ M6P) receptor is released by cells in culture and circulates in the serum. It retains its ability to bind IGF-II and blocks IGF-II-stimulated DNA synthesis in isolated rat hepatocytes. Because these cells are not nor

Mannose 6-phosphate/insulin-like growth
✍ J. Keith Killian; Yoshihiko Oka; Hong-Seok Jang; Xialong Fu; Robert A. Waterland πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 205 KB

M6P/IGF2R encodes a multifunctional protein involved in lysosomal enzyme trafficking, fetal organogenesis, tumor suppression, and cytotoxic T cell-induced apoptosis. M6P/IGF2R is imprinted and expressed only from the maternally inherited allele in marsupials and rodents. In contrast, humans were ini

Insulin-induced redistribution of the in
✍ Laurence Villevalois-Cam; Khadija Tahiri; GeneviΓ¨ve Chauvet; Bernard Desbuquois πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 217 KB πŸ‘ 1 views

The ability of acute insulin treatment to elicit a redistribution of the liver insulin-like growth factor-II/ mannose 6-phosphate (IGF-II/M6P) receptor has been studied in rats, using cell fractionation. Injection of insulin (0.4 -50 g) led to a time-and dose-dependent decrease in IGF-II binding act