Demonstration of plasma proteinase inhibitors in β2-microglobulin amyloid deposits
✍ Scribed by Campistol, Josep M; Shirahama, Tsuranobu; Abraham, Carmela R; Rodgers, Orville G; Solé, Manel; Cohen, Alan S; Skinner, Martha
- Book ID
- 109882198
- Publisher
- Nature Publishing Group
- Year
- 1992
- Tongue
- English
- Weight
- 1014 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0085-2538
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📜 SIMILAR VOLUMES
## Background: Systemic amyloidosis occurs as a result of amyloid deposition in various tissues. the amyloid fibrils in systemic amyloidosis have been reported to originate from immunoglobulin light chains. ## Objective: We studied the composition of amyloid fibrils from two patients with plasma
Among various amyloidogenic proteins, beta(2)-microglobulin (beta2-m) responsible for dialysis-related amyloidosis is a target of extensive study because of its clinical importance and suitable size for examining the formation of amyloid fibrils in comparison with protein folding to the native state