Acrylonitrile biotransformation in rats,
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I. Gut; J. Nerudová; J. Kopecký; V. Holeček
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Article
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1975
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Springer-Verlag
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English
⚖ 733 KB
Female Wistar rats, conventional albino mice, and Chinese hamsters were given a single dose of acrylonitrile, 0.5 or 0.75 mM/kg body weight. The elimination in the urine of thiocyanate, which is the main metabolite of acrylonitrilc, indicated a decreasing proportion of biotransformation after oral (