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Delivery systems: a vaccine strategy for overcoming mucosal tolerance?

✍ Scribed by Mann, Jamie FS; Acevedo, Reinaldo; Campo, Judith del; Pérez, Oliver; Ferro, Valerie A


Book ID
118011336
Publisher
Expert Reviews
Year
2009
Tongue
English
Weight
288 KB
Volume
8
Category
Article
ISSN
1476-0584

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Gram-positive commensal bacteria for muc
✍ Vincent A Fischetti; Donata Medaglini; Gianni Pozzi 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 757 KB

To avoid the use of engineered pathogens for vaccine delivery, systems have been developed that allow the expression of heterologous antigens in commensal Gram-positive bacteria. In some cases, both a serum IgG and secretory IgA response are induced to the recombinant protein after vaccination, veri