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Delivery of human acetylcholinesterase by adeno-associated virus to the acetylcholinesterase knockout mouse

✍ Scribed by Anna Hrabovska; Ellen G. Duysen; Jeffrey D. Sanders; L. Charles Murrin; Oksana Lockridge


Book ID
113517219
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
226 KB
Volume
157-158
Category
Article
ISSN
0009-2797

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## Abstract ## Background Vascular gene therapy requires safe and efficient gene transfer __in vivo__. Recombinant adeno‐associated virus (AAV) is a promising viral vector but its use in the vasculature has produced conflicting results and serotypes other than AAV2 have not been intensively studie