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Delivery of Brain-Derived Neurotrophic Factor via Nose-to-Brain Pathway

✍ Scribed by Siva Ram Kiran Vaka; Sathyanarayana Narasimha Murthy; Anna Balaji; Michael A. Repka


Publisher
Springer US
Year
2011
Tongue
English
Weight
222 KB
Volume
29
Category
Article
ISSN
0724-8741

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Delivery of nerve growth factor to brain
✍ Siva Ram Kiran Vaka; S.M. Sammeta; Lainy B. Day; S. Narasimha Murthy πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 157 KB

The main objective of the study was to investigate the efficacy of chitosan to facilitate brain bioavailability of intranasally administered nerve growth factor (NGF). In vitro permeability studies and electrical resistance studies were carried out across the bovine olfactory epithelium using Franz