## Abstract The induction of the immediate early gene __Arc__ is strongly implicated in synaptic plasticity. Although the role of ERK has been demonstrated, the regulation of __Arc__ expression is largely unknown. In this study, we investigated the major signaling pathways underlying brainβderived
Calcium regulation of the brain-derived neurotrophic factor gene
β Scribed by Steven Finkbeiner*
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 107 KB
- Volume
- 57
- Category
- Article
- ISSN
- 1420-682X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Brain-derived neurotrophic factor (BDNF) enhances synaptic plasticity and neuron function. We have reported that voluntary exercise increases BDNF mRNA levels in the hippocampus; however, mechanisms underlying this regulation have not been defined. We hypothesized that medial septal cholinergic and/
sequence of this region in a larger number of subjects, including other ethnics, may provide more information.
Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are structurally related survival and differentiation factors for distinct sets of peripheral and central neurons. The regulation of NGF gene expression has been extensively studied in L929 mouse fibroblasts. L929 cells also expr