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Deletion polymorphism in the gene for angiotensin converting enzyme is associated with elevated fasting blood glucose levels

✍ Scribed by Adriana Zingone; Andrea Dominijanni; Evelina Mele; Onorina Marasco; Franca Melina; Pasquale Minchella; Barbara Quaresima; Maria Teresa Tiano; Agostino Gnasso; Arturo Pujia; Nicola Perrotti

Publisher: Springer
Year: 1994
Tongue: English
Weight: 195 KB
Volume: 94
Category: Article
ISSN: 0340-6717
DOI: 10.1007/bf00202873

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✦ Synopsis

The frequency and distribution of angiotensin converting enzyme insertion/deletion (ACE I/D) polymorphism, and its association with other known risk factors for coronary atherosclerosis, has been studied, in a normal south Italian population. Subjects homozygous for deletion showed elevated fasting blood glucose levels when compared with subjects homozygous for insertion. The difference was consistent with an increased number of type 2 diabetics among the former group of subjects.

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