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Deletion of fibroblast growth factor receptor 2b (Fgfr2b) gene results in anorectal malformation in mouse

✍ Scribed by T.J. Fairbanks; R.C. Kanard; S.P. De Langhe; F.G. Sala; K.D. Anderson; D. Warburton; S. Bellusci; R.C. Burns


Book ID
116701142
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
117 KB
Volume
114
Category
Article
ISSN
0022-4804

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Fibroblast growth factors may play an important role in the differential growth of the skull, brain, and facial prominences. In order to understand the role of FGFs in vivo, we have analyzed the competency of head mesenchyme to respond to FGFs via expression of the high affinity receptors FGFR1, 2,