Fibroblast growth factors may play an important role in the differential growth of the skull, brain, and facial prominences. In order to understand the role of FGFs in vivo, we have analyzed the competency of head mesenchyme to respond to FGFs via expression of the high affinity receptors FGFR1, 2,
β¦ LIBER β¦
Overexpression of fibroblast growth factor receptors FGFR1 and FGFR2 in renal cell carcinoma
β Scribed by Tsimafeyeu, Ilya; Demidov, Lev; Stepanova, Eugenia; Wynn, Nigel; Ta, Hung
- Book ID
- 120072075
- Publisher
- Informa plc
- Year
- 2011
- Tongue
- English
- Weight
- 472 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0036-5599
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## Abstract Activation of fibroblast growth factor (FGF) receptors (FGFRs) both by FGFs and by the neural cell adhesion molecule (NCAM) is crucial in the development and function of the nervous system. We found that FGFR substrate 2Ξ± (FRS2Ξ±), Src homologous and collagen A (ShcA), and phospholipaseβ