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Deletion of chromosome 6q in two cases of acute myeloblastic leukemia and a review of the literature

โœ Scribed by Jouji Hirata; Yasunobu Abe; Fumihiro Taguchi; Hiroshi Takatsuki; Junji Nishimura; Hajime Nawata

Book ID
119105365
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
921 KB
Volume
58
Category
Article
ISSN
0165-4608

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## Abstract Double minutes (dmin) are small, paired chromatin bodies that lack a centromere and represent a form of extrachromosomal gene amplification. Although they have been found in a variety of solid tumors, their presence in hematological malignancies, especially acute myeloid leukemia (AML),