Double minute chromosomes in monoblastic
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Leno Thomas; Judith Stamberg; Ivana Gojo; Yi Ning; Aaron P. Rapoport
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Article
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2004
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John Wiley and Sons
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English
β 153 KB
π 2 views
## Abstract Double minutes (dmin) are small, paired chromatin bodies that lack a centromere and represent a form of extrachromosomal gene amplification. Although they have been found in a variety of solid tumors, their presence in hematological malignancies, especially acute myeloid leukemia (AML),