Deletion of 2p: A cytogenetic and clinical update
β Scribed by Neidich, Julie ;Zackai, Elaine ;Aronson, Margaret ;Emanuel, Beverly S. ;Opitz, John M. ;Reynolds, James F.
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 685 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0148-7299
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Chromosome analysis with high-resolution banding showed a small de novo interstitial deletion of chromosome 2(p21 -p22.2) in an infant with holoprosencephaly. This is the first such observation. There is a well-known association with abnormalities of chromosome 13 (most commonly trisomy 13, but also
Please note that Figure 2A needed correction. [A] FISH using subtelomere probes [TelVysion 2p Spectrum green (VIJyRM2052) and TelVysion 2q Spectrum orange (VIJyRM2123)] from Abbott Molecular. The legend is correct; however, the chromosome on the left should have a red signal designated with q and n