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Deletion mapping of chromosomes 8, 10, and 16 in human prostatic carcinoma

✍ Scribed by Ulf S. R. Bergerheim; Kazuto Kunimi; Dr. V. Peter Collins; Peter Ekman


Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
738 KB
Volume
3
Category
Article
ISSN
1045-2257

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Deletion mapping of chromosomes 8, 10, a
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In an allelotyping study of prostatic carcinoma, we found the highest frequency of allelic deletions on chromosomes 8, 10, 16, and 18. In all cases with allelic deletions, at least one of the chromosomes 8, 10, and 16 were involved. A detailed deletion mapping of these chromosomes in I 8 cases was c

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Frequent losses of heterozygosity observed at several chromosomal loci in primary lung cancers have indicated the existence of several tumor suppressor genes associated with this type of cancer. We have examined loss of heterozygosity on chromosomal arm 8p in 49 cases of non-small cell lung carcinom