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Delayed resolution of acute inflammation during zymosan-induced arthritis in leptin-deficient mice

✍ Scribed by Eiva Bernotiene, Gaby Palmer, Dominique Talabot-Ayer…

Book ID
120707126
Publisher
BioMed Central
Year
2004
Tongue
English
Weight
400 KB
Volume
6
Category
Article
ISSN
1478-6354

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Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: Exacerbation of joint inflammation in STAT-1 gene–knockout mice
✍ Alfons S. K. de Hooge; Fons A. J. van de Loo; Marije I. Koenders; Miranda B. Ben 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 594 KB

## Abstract ## Objective STAT proteins play an important role in cytokine signaling. Some investigators have reported preferential activation of STAT‐1, and others have reported preferential activation of STAT‐3, in response to endogenous interleukin‐6 (IL‐6), in patients with rheumatoid arthritis