Characterization of mice deficient in in
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Ping Li; Hamish Allen; Subhashis Banerjee; Tara Seshadri
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Article
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1997
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John Wiley and Sons
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English
⚖ 66 KB
👁 1 views
Interleukin-1b converting enzyme (ICE) processes the inactive proIL-1b to the proinflammatory mature IL-1b. ICE belongs to a family of cysteine proteases that have been implicated in apoptosis. To address the biological functions of ICE, we generated ICE-deficient mice through gene targeting technol