Statins induce angiogenesis, neurogenesi
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Jieli Chen; Zheng Gang Zhang; Yi Li; Ying Wang; Lei Wang; Hao Jiang; Chenling Zh
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Article
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2003
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John Wiley and Sons
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English
β 738 KB
## Abstract We demonstrate that the 3βhydroxyβ3βmethylβglutarylβcoenzyme A (HMGβCoA) reductase inhibitors atorvastatin and simvastatin enhance functional outcome and induce brain plasticity when administered after stroke to rats. With atorvastatin treatment initiated 1 day after stroke, animals exh