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Delayed drug hypersensitivity: models of T-cell stimulation

✍ Scribed by Jacqueline Adam; Werner J. Pichler; Daniel Yerly


Book ID
108642593
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
750 KB
Volume
71
Category
Article
ISSN
0306-5251

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Cellular mechanisms of T cell mediated d
✍ Basil O Gerber; Werner J Pichler πŸ“‚ Article πŸ“… 2004 πŸ› Elsevier Science 🌐 English βš– 135 KB

Noncovalent drug presentation leads to the activation of drug-specific T cells. In some patients with hypersensitivity, such a response occurs within hours even upon the first exposure to the drug. Thus, the reaction to the drug might not be due to a classical, primary response, but rather mediated