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Dehydropeptide Production in the Radiolysis of Solid Peptides : a Radiolytic Synthesis of Pyrazine Derivatives from Cyclic Dipeptides

โœ Scribed by KLAND-ENGLISH, MATHILDE; GARRISON, WARREN M.


Book ID
109626812
Publisher
Nature Publishing Group
Year
1963
Tongue
English
Weight
352 KB
Volume
197
Category
Article
ISSN
0028-0836

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On the use of PyAOP, a phosphonium salt
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Phosphonium derivatives of HOAt such as PyAOP are useful for the solid-phase preparation of a range of peptides that include those incorporating hindered amino acids, difficult short sequences, and cyclic peptides. An advantage relative to uronium salts is that excess PyAOP does not undergo the detr