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Deguelin inhibits expression of IκBα protein and induces apoptosis of B-CLL cells in vitro

✍ Scribed by Geeraerts, B; Vanhoecke, B; Vanden Berghe, W; Philippé, J; Offner, F; Deforce, D

Book ID
110058298
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
440 KB
Volume
21
Category
Article
ISSN
0887-6924

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## Abstract The nuclear factor (NF)‐κB family of transcription factors plays important roles in the regulation of many activities of neuronal cells, such as synaptic transmission, inflammation, neuroprotection, and neurotoxicity. In resting cells, NF‐κB activity is present both in the cytoplasm, as