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Degradation of glyceraldehyde-3-phosphate dehydrogenase triggered by 4-hydroxy-2-nonenal and 4-hydroxy-2-hexenal

✍ Scribed by Yukihiro Tsuchiya; Mitsune Yamaguchi; Toshiyuki Chikuma; Hiroshi Hojo


Book ID
116177349
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
470 KB
Volume
438
Category
Article
ISSN
0003-9861

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The hepatic oxidation of ethanol has been demonstrated to cause peroxidation of cellular membranes, resulting in the production of aldehydes that are substrates for hepatic aldehyde dehydrogenases. It was the purpose of this study to evaluate the cooxidation of the lipid peroxidation product, truns-