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Degradation of a cAMP-binding protein is inhibited by human c-Ha-ras gene products

✍ Scribed by Takaki Hiwasa; Shigeru Sakiyama; Shigeru Noguchi; Jong-Myung Ha; Tatsuo Miyazawa; Shigeyuki Yokoyama


Book ID
115760305
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
885 KB
Volume
146
Category
Article
ISSN
0006-291X

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## Abstract MCF‐ 10A is a spontaneously immortalized, non‐transformed human mammary epithelial cell line. We have recently obtained MCF‐ 10A clones (MCF‐ 1OA HE cells) that are transformed following over‐expression of both a human point‐mutated c‐Ha‐__ras__ and the c‐__erb__B‐2 proto‐oncogenes. Two