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Deglyco GABA-Gly-desacetamidobleomycin A2: a simplified synthetic model for bleomycin A2

โœ Scribed by Dale L. Boger; Royce F. Menezes; Qun Dang; Wenjin Yang

Book ID
108477096
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
498 KB
Volume
2
Category
Article
ISSN
0960-894X

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โœ Vasanthakumar Rajappan; Ramachandra S Hosmane ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 87 KB

A model study for a novel approach to the synthesis of 2-carboxyinosines has been described. The synthesis of 9-benzyl-2-carboxyhypoxanthine (I), a model for 2-carboxyinosine, was achieved in four steps starting from 1-benzyl-5-nitroimidazole-4-carboxylic acid. Also reported is the synthesis of 9-be