✦ LIBER ✦

Defining the therapeutic window in a severe animal model of spinal muscular atrophy

✍ Scribed by Robbins, K. L.; Glascock, J. J.; Osman, E. Y.; Miller, M. R.; Lorson, C. L.

Book ID: 121676935
Publisher: Oxford University Press
Year: 2014
Tongue: English
Weight: 618 KB
Volume: 23
Category: Article
ISSN: 0964-6906
DOI: 10.1093/hmg/ddu169

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Pathogenesis, animal models and therapeu

Pathogenesis, animal models and therapeutics in Spinal and bulbar muscular atrophy (SBMA)

✍ Masahisa Katsuno; Hiroaki Adachi; Masahiro Waza; Haruhiko Banno; Keisuke Suzuki; 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 481 KB

Multiple therapeutic effects of valproic

Multiple therapeutic effects of valproic acid in spinal muscular atrophy model mice

✍ Li-Kai Tsai; Ming-Shiun Tsai; Chen-Hung Ting; Hung Li 📂 Article 📅 2008 🏛 Springer 🌐 English ⚖ 627 KB

Severe depletion of mitochondrial DNA in

Severe depletion of mitochondrial DNA in spinal muscular atrophy

✍ Alexandra Berger; Johannes A. Mayr; David Meierhofer; Ulrike Fötschl; Reginald B 📂 Article 📅 2003 🏛 Springer-Verlag 🌐 English ⚖ 284 KB

Analysis of a read-through promoting com

Analysis of a read-through promoting compound in a severe mouse model of spinal muscular atrophy

✍ Virginia B. Mattis; Cheng-Wei Tom Chang; Christian L. Lorson 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 344 KB

Immunocytochemical abnormalities in a mo

Immunocytochemical abnormalities in a mouse model of spinal muscular atrophy

✍ Mandler, Raúl N.; Allgood, Pam C. 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 125 KB

Mitochondrial dysfunction in a neural ce

Mitochondrial dysfunction in a neural cell model of spinal muscular atrophy

✍ Gyula Acsadi; Icksoo Lee; Xingli Li; Magomed Khaidakov; Alena Pecinova; Graham C 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 255 KB

## Abstract Mutations of the survival motor neuron (SMN) gene in spinal muscular atrophy (SMA) lead to anterior horn cell death. The cause is unknown, but motor neurons depend substantially on mitochondrial oxidative phosphorylation (OxPhos) for normal function. Therefore, mitochondrial parameters