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Deficiency of thrombospondin-1 reduces Th17 differentiation and attenuates experimental autoimmune encephalomyelitis

✍ Scribed by Kaiyong Yang; Jose L. Vega; Muhamed Hadzipasic; Jean Pierre Schatzmann Peron; Bing Zhu; Yijun Carrier; Sharmila Masli; Luiz Vicente Rizzo; Howard L. Weiner


Book ID
116614191
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
676 KB
Volume
32
Category
Article
ISSN
0896-8411

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## Abstract High‐mobility group box 1 (HMGB1), a non‐histone nuclear protein, has been implicated in cardiovascular diseases. Dilated cardiomyopathy (DCM), one of the leading causes of heart failure, is often caused by coxsackievirus B3‐triggered myocarditis and promoted by the post‐infectious auto