๐”– Bobbio Scriptorium
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Deferred therapy in patients with advanced disease

โœ Scribed by PH Smith


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
398 KB
Volume
71
Category
Article
ISSN
0008-543X

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โœฆ Synopsis


Disease that is known to have extended beyond the prostatic capsule is unlikely to be cured by radical surgical excision, although the primary tumor may be controlled by external irradiation. The development of pro- gressive (metastatic) disease is common and may be retarded by hormonal therapy. The timing of such treatment and the debate about monotherapy versus total androgen ablation has not been resolved fully.


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Bleomycin was used to treat 31 patients with a variety of advanced, previously treated malignancies, with particular emphasis o n Hodgkin's disease and epidermoid cancers. Bleomycin was administered either twice weekly, 15 mg per dose, or in 5-day courses, 105 mg total dose per course. Three of 10 p