Defensins
β Scribed by Ganz T.
- Book ID
- 127398735
- Year
- 2000
- Tongue
- English
- Weight
- 159 KB
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
Defensins are a family of variably cationic 3-5 kDa peptides with a conserved motif of six disulfide-linked cysteines. They are expressed in host defense settings (in phagocytes and epithelia) and display a broad spectrum of antimicrobial activity. The production of many defensins is constitutive but others are induced by infectious or inflammatory stimuli. Some defensins are chemoattractant for monocytes, lymphocytes, and dendritic cells.
π SIMILAR VOLUMES
Defensins are widely distributed and abundant 3-4 kDa antimicrobial peptides that are variably cationic and contain six disulfide-paired cysteines. Three structurally distinct peptide families have been identified: 'classical' defensins, wefensins and insect defensins. In many animal species, defens