Defensins are widely distributed and abundant 3-4 kDa antimicrobial peptides that are variably cationic and contain six disulfide-paired cysteines. Three structurally distinct peptide families have been identified: 'classical' defensins, wefensins and insect defensins. In many animal species, defens
β¦ LIBER β¦
Defensins
β Scribed by Tomas Ganz; Michael E. Selsted; Robert I. Lehrer
- Book ID
- 114791237
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 963 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0902-4441
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Defensins are a family of variably cationic 3-5 kDa peptides with a conserved motif of six disulfide-linked cysteines. They are expressed in host defense settings (in phagocytes and epithelia) and display a broad spectrum of antimicrobial activity. The production of many defensins is constitutive bu
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