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Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells

✍ Scribed by Leland Hartwell


Book ID
119064277
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
534 KB
Volume
71
Category
Article
ISSN
0092-8674

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## Abstract Radiation induced genomic instability can be described as the increased rate of genomic alterations occurring in the progeny of an irradiated cell. Its manifestations are the dynamic ongoing production of chromosomal rearrangements, mutations, gene amplifications, transformation, micros